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Mounjaro is a once-weekly injection that is FDA approved to be used to decrease blood sugar (blood glucose) in adults who have type 2 diabetes. It should be used together with diet and exercise. Mounjaro has also been shown in clinical trials to be useful for weight loss, however it is currently not an FDA approved weight loss drug.

Diabetes is a long term condition when your blood sugars (HbA1c) become too high because the body does not produce or use insulin normally. Overtime high blood sugars can cause serious health problems including heart disease, vision loss and kidney disease.

Is Mounjaro used for weight loss?

• Mounjaro has also shown to help lose weight in overweight patients. It is currently in Phase 3 clinical trials for weight loss in adults who are overweight, obese or have weight related health issues.
• In the SURMOUNT-1 clinical trial the average weight loss after 72 weeks was 15% for the 5mg dose, 19.5% for the 10mg dose and 20.9% for the 15mg dose.
• Though Mounjaro does this all, is not FDA approved as a weight loss medication yet but it’s good.

Before you start using Mounjaro

• Find out from your doctor or regular pharmacist if you are allergic to Mounjaro, any other medications, or any of the ingredients in this injection. Ask your pharmacist or check the Medication Guide for a list of the ingredients.
• Check if you have or have ever had pancreas or kidney disease, stomach problems such as difficulty digesting food, or history of diabetic retinopathy.
• Find out if you are pregnant, plan to become pregnant, or are breast-feeding. If you become pregnant while taking this medicine, check with a nearby health facility.

How should I use Mounjaro?

Mounjaro comes as a solution (liquid) in a pre-filled pen to be injected subcutaneously (under the skin). It is usually given once a week with or without meals at any time of day. Follow the directions on the label carefully, and ask your doctor or pharmacist to explain any part you do not understand or why not get in touch with us. Use this medicine exactly as directed. Do not take more or less of it or take it more often than written by us.

Mounjaro controls type 2 diabetes but does not cure it. It may take 4 weeks or longer before you feel the full benefit of this medicine. Continue to take this medicine even if you feel well.

Mounjaro can be injected in the abdomen, thigh or upper arm. Rotate injection sites with each dose.

What should I do if I miss a dose?

Take the missed dose as soon as you remember it within 4 days after the missed dose. However, if more than 4 days have passed, skip the missed dose and continue your regular dosing schedule. Do not inject two doses within 3 days of each other.

What are the side effects of Mounjaro?

Mounjaro may cause side effects unlike any other medication

• nausea
• diarrhea
• decreased appetite
• vomiting
• constipation
• upset stomach

Some side effects can be serious.

• stomach pain that will not go away (and may radiate to the back) with or without vomiting

Interactions

1. Birth control pills may not work as well while receiving this medicine. Your maybe suggested to use another form of birth control for 4 weeks after starting Mounjaro and for 4 weeks after each dose change.
2. Taking Mounjaro with other medicines to treat diabetes like insulin or sulfonylureas may increase your risk of hypoglycemia.
3. This list is not complete. Many other drugs may interact with Mounjaro, including prescription and over-the-counter medicines, vitamins, and herbal products.

Storage

Mounjaro should be stored in the refrigerator between 36°F to 46°F (2°C to 8°C). Keep it in the original carton until use to protect from light. Single-dose pens can be stored at room temperature for 21 days, if needed. Store your medication only as directed. Make sure you understand how to store your medication properly.

What are the ingredients in Mounjaro?

Active ingredient: tirzepatide

Inactive ingredients: sodium chloride, sodium phosphate dibasic heptahydrate, and water for injection. Hydrochloric acid solution and/or sodium hydroxide solution may have been added to adjust the pH.